Ozempic Butt 2026: What It Is And How It Can Be Avoided & Fixed

Ozempic butt refers to the deflated, sagging or flat appearance of the buttocks that occurs after significant weight loss from GLP-1 receptor agonist medications like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound). This phenomenon happens when rapid fat loss outpaces your skin’s ability to retract, combined with muscle loss that removes the underlying structure supporting your buttocks.

According to research published in PubMed, approximately 40% of total weight lost on semaglutide medications can come from lean body mass, including muscle. This significant amount of fat and muscle loss affects body proportions and can leave many patients experiencing Ozempic butt – even after achieving their weight loss goals.

The good news is that with the right treatment plan and prevention strategies, you can avoid Ozempic butt or restore volume if you’re already experiencing unwanted changes to your body shape.

TL;DR

• Ozempic butt is the loss of volume, shape and firmness in the buttocks following rapid weight loss from GLP-1 medications like Ozempic, Wegovy or Mounjaro. 
• Up to 40% of weight lost on semaglutide can come from lean muscle mass including the gluteal muscles that shape your rear end. 
• Prevention strategies include gradual weight loss (1-2 lbs/week), high protein intake (1.6g/kg bodyweight daily) and consistent resistance training targeting the glutes. 
• Treatment options range from strength training and non surgical procedures like Sculptra injections to surgical interventions like Brazilian Butt Lift (BBL) for severe cases.

What Is Ozempic Butt? – Causes & Symptoms

Ozempic butt develops when rapid weight loss causes your buttocks to lose both fat and muscle mass faster than your skin elasticity can adapt. The result is sagging skin, lost volume and changes to your body composition that affect how your clothes fit and how you feel confident in your appearance.

Sagging skin and changes in appearance can also occur in other areas such as the face (known as “Ozempic face”), breasts, arms and thighs due to non-discriminatory weight loss from these weight loss medications. Additionally, gastrointestinal side effects of Ozempic can include nausea, vomiting, diarrhea, constipation, abdominal pain, and bloating.

Why Ozempic Causes Butt Sagging

Rapid fat loss of 15-25% body weight exceeds your skin’s natural ability to contract. Research from the National Institutes of Health shows that skin laxity after weight loss occurs because of damage to collagen and elastin fibers which prevents skin retraction.

Several factors influence severity: genetics determine where fat is stored and lost and older adults may face more significant issues with skin laxity following weight loss due to naturally declining collagen production. Women over 40 losing 50+ pounds face approximately 70% risk of experiencing noticeable Ozempic butt.

Ozempic Weight Loss vs Normal Weight Loss

The key difference lies in the speed of weight loss:

• Ozempic weight loss: You lose 4-8 lbs/month and thus, skin can’t shrink fast enough
• Traditional diet/exercise: You lose 1-2 lbs/week so skin adapts gradually

Without proper protein intake and exercise, up to 40% of weight lost on semaglutide medications can come from lean muscle mass according to the Endocrine Society. This muscle loss compounds the aesthetic impact on your buttocks.

How to Avoid Ozempic Butt – Prevention Strategies

Prevention is significantly more effective than trying to treat Ozempic butt after it develops. Here’s what works:

Gradual weight loss is recommended to minimize the risk of developing Ozempic butt by allowing the body to adjust. The CDC recommends losing 1-2 pounds per week for sustainable results.

Best Glute Exercises During Ozempic

Strength training is essential to maintain muscle mass and improve skin texture beneath the surface. As per studies, resistance training can actually rejuvenate aging skin by improving elasticity and dermal thickness.

Focus on these exercises targeting your gluteal muscles:

1. Hip thrusts (3×12 reps) – maximum glute activation
2. Bulgarian split squats (3×10 per leg) – builds strength and balance
3. Cable kickbacks (3×15 reps) – targets glute medius
4. Resistance band work – daily glute activation

Nutrition to Prevent Sagging Skin

High protein intake is critical to support muscle preservation during calorie deficits while losing weight. Research confirms that protein intake exceeding 1.3g/kg/day helps maintain muscle mass during weight loss.

• Protein: 1.6g/kg bodyweight daily (120-150g for most adults)
• Collagen peptides: 15g/day of Types I and III
• Healthy fats: Omega-3s from fatty fish support skin health
• Hydration: Adequate water intake maintains skin elasticity

How to Fix Ozempic Butt – Treatment Options

If you’re already experiencing Ozempic butt, multiple treatment options exist depending on severity:

12-Week Glute Rebuilding Program

A structured approach to restore volume and muscle tone:

• Week 1-4: Bodyweight squats, glute bridges and  protein 120g daily 
• Week 5-8: Add hip thrusts 3×12 and creatine 5g for muscle function 
• Week 9-12: Progress to heavy deadlifts and consult aesthetic specialists

Non-Surgical Butt Restoration

For those seeking minimally invasive procedures, several advanced non surgical treatments can help restore volume without surgery:

• EmSculpt: Delivers approximately 25,000 muscle contractions per session, building muscle in the treated area
• Sculptra: A collagen-stimulating injectable filler that gradually restores lost volume over 2-4 sessions, with results lasting up to two years according to board certified plastic surgeons
• Radiofrequency skin tightening treatments: Morpheus8 and similar devices stimulate collagen for a lifted appearance
• Traditional HA fillers: Generally don’t last in high-motion areas like the buttocks

For severe cases, cosmetic procedures such as fat transfer (Brazilian Butt Lift) or body contouring surgery may be necessary. A board certified plastic surgeon can create a personalized plan based on your specific needs and help you achieve a toned appearance with better buttocks proportions.

Ozempic Butt Risk Factors 

Understanding your risk profile helps you take preventive action:

Ozempic butt can affect individuals of all ages but older individuals may experience more pronounced effects due to natural aging and reduced skin elasticity. Your body weight before starting treatment, genetics and commitment to resistance training all influence outcomes.

Prevention Priority: Slow weight loss (1-2lb/week max) combined with consistent glute-focused strength training offers the best protection against unwanted changes to your body shape.

References & Resources 

• Ozempic Prescribing Information 
• Effect of semaglutide on lean mass
• Gastrointestinal adverse events associated with semaglutide