Save 10% off on your first order with coupon code: PANDA10

Saxenda for weight loss – Dosing Chart, Side Effects & More

Published On: October 4, 2024

Saxenda is a doctor-prescribed prescription used to aid in weight reduction. It’s intended to help grown-ups who are struggling with obesity or being overweight, particularly individuals who additionally have weight-related medical issues.

Unlike convenient solution diets or enhancements, Saxenda simulates work natural hormone in your body that helps regulate appetite and digestion. This can assist you with feeling fuller for longer and ultimately consuming fewer calories.

What Type of Medication is Saxenda?  (Saxenda Ingredients & Instructions)

Saxenda is classified as a glucagon-like peptide-1 (GLP-1) agonist. This means it mimics the actions of a naturally occurring hormone in your body that helps regulate blood sugar, appetite, and digestion.  

Saxenda Ingredients

The active ingredient in Saxenda is liraglutide. This is a synthetic version of GLP-1.  

How to Use Saxenda

  • Injection: Saxenda is administered as a daily subcutaneous injection (under the skin).  
  • Dosage: The starting dose is typically low and gradually increases over time.
  • Timing: Saxenda can be injected at any time of day, with or without food.

How Does Saxenda Work? (Mechanism)

Saxenda simulates a naturally occurring hormone called glucagon-like peptide-1 (GLP-1). This hormone plays a key role in regulating appetite and digestion.  

Here’s a breakdown of its mechanism of action:

  • Appetite Suppression: Saxenda helps reduce hunger and cravings by imitating the actions of GLP-1. This can make it easier to stick to a reduced-calorie diet.  
  • Slower Stomach Emptying: Saxenda slows down the rate at which food leaves your Stomach, helping you feel fuller for longer. This can lead to reduced calorie intake.  

Moreover, Saxenda can also stimulate the release of insulin, a crucial hormone in managing blood sugar levels. This feature is particularly beneficial for individuals with type 2 diabetes, providing them with an additional tool in their management plan. By combining these actions, Saxenda can assist in weight loss when used in conjunction with a healthy diet and regular exercise.  

Is Saxenda FDA-Approved for Weight Loss?

While it was initially approved to help manage type 2 diabetes, subsequent studies have shown its effectiveness in promoting weight loss. The FDA expanded its approval to include chronic weight management in adults with obesity or overweight who have at least one weight-related condition.

Saxenda (liraglutide) is specifically FDA-approved for chronic weight management in adults who meet certain criteria:

  • Adults with obesity: A BMI of 30 or higher.
  • Adults who are overweight: A BMI of 27 or higher with at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or high cholesterol.

It’s crucial to remember that Saxenda is not a magic solution. It’s most effective with a healthy diet and regular physical activity.

While Saxenda was initially approved to treat type 2 diabetes, its weight loss benefits led to the expanded approval for chronic weight management.

Saxenda Dosing Schedule

Saxenda pens are available in pre-filled doses, making them convenient for patients to administer the same dose. The dosing schedule is designed to increase the dosage to minimize side effects gradually.

  • Starting Dose: The initial dose is typically 0.6 mg daily for one week.
  • Dose Escalation: The dose is increased by 0.6 mg weekly until the target maintenance dose is reached.
  • Maintenance Dose: The recommended maintenance dose for adults is 3.0 mg per day. However, your doctor might sometimes adjust this based on your response and tolerance.
  • Highest Dose: The highest available dose of Saxenda is 3.0 mg daily.

Lowest Dose: The lowest available dose is 0.6 mg per day, also the starting dose.

Important Note: This is a general dosing guideline. A healthcare professional should determine the specific dosing schedule for an individual patient. Weight, medical conditions, and individual response can influence the dosing regimen.

What Happens When You Stop Taking Saxenda?

Stopping Saxenda doesn’t mean the end of your weight loss journey. It’s a transition period that requires careful planning and dedication.

  • Gradual Reduction: If you decide to stop Saxenda, consider a gradual reduction in dosage rather than quitting abruptly. This can help your body adjust more smoothly.
  • Lifestyle Adjustments: Focus on building sustainable lifestyle changes. Prioritize regular exercise, a balanced diet, and adequate sleep.
  • Support System: Surround yourself with supportive friends, family, or join weight loss groups. Sharing experiences and challenges can be motivating.
  • Professional Guidance: Consult a registered dietitian or a weight management specialist for personalized advice.
  • Mindful Eating: Practice mindful eating to develop a healthier relationship with food. Pay attention to hunger cues and avoid emotional eating.
  • Regular Check-ups: Schedule regular follow-up appointments with your healthcare provider to monitor your progress and address concerns.

Saxenda Side Effects

Saxenda, like any medication, can cause side effects. It’s essential to be aware of these potential side effects and consult your healthcare provider if you experience any concerns.

Common Side Effects

These are the most frequently reported side effects:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Headache
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Injection site reactions

Mild Side Effects

In addition to the common side effects, some people may experience milder side effects, such as:

  • Bloating
  • Indigestion
  • Heartburn
  • Dry mouth
  • Sleep disturbances

Serious Side Effects

While less common, some serious side effects can occur. If you experience any of these, seek medical attention immediately:

  • Pancreatitis (inflammation of the pancreas)
  • Gallbladder problems
  • Low blood sugar (hypoglycemia)
  • Increased heart rate
  • Kidney problems
  • Serious allergic reactions
  • Depression or suicidal thoughts

Missed Dose Side Effects

Missing a dose of Saxenda is generally not a cause for concern. Resume your regular dosing schedule. However, if you consistently miss doses, it may impact the medication’s effectiveness.

Overdose Side Effects

Overdosing on Saxenda can lead to an increase in side effects, particularly nausea, vomiting, and diarrhea. If you suspect an overdose, contact your healthcare provider or seek medical attention immediately.

Saxenda Warning & Precautions

Saxenda is a prescription medication used for weight management. While it can be effective, understanding the potential risks and who should avoid them is essential.

Who Should Not Use Saxenda?

  • People with a history of medullary thyroid cancer (MTC) or a family history of MTC: There’s a potential link between Saxenda and this type of thyroid cancer.
  • People with severe kidney problems: Saxenda might worsen kidney function.
  • People with diabetic ketoacidosis: This is a serious condition that requires immediate medical attention.
  • Children under 18: Saxenda is only approved for adults and adolescents aged 12 to 17.
  • Allergy to liraglutide or any ingredient in Saxenda: Avoid if you have known allergies.

Important Precautions Before Using Saxenda

  • Inform your doctor about your medical history: This includes conditions like diabetes, pancreatitis, thyroid problems, kidney disease, and any other health issues.
  • Discuss medications: Tell your doctor about all medications, including over-the-counter drugs, vitamins, and herbal supplements.
  • Pregnancy and breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Alcohol consumption: Excessive alcohol intake can increase the risk of liver damage.
  • Regular monitoring: Regular check-ups are essential to monitor your health using Saxenda.

Serious Side Effects

  • Pancreatitis: Symptoms include severe abdominal pain, nausea, and vomiting.
  • Gallbladder problems: This can lead to gallstones.
  • Low blood sugar: Especially if you’re also taking diabetes medications.
  • Increased heart rate: Monitor your heart rate regularly.
  • Kidney problems: This can worsen existing kidney issues.
  • Allergic reactions: Symptoms include rash, itching, swelling, and difficulty breathing.
  • Thyroid cancer: There’s a potential increased risk, especially for those with a family history of MTC.
  • Depression or suicidal thoughts: Contact your doctor immediately if you experience these symptoms.

Saxenda Alternatives 

While Saxenda is a popular option for weight management, it might only be suitable for some. Let’s explore alternatives in more detail:

Medication-Based Alternatives

  • GLP-1 Agonists: These medications mimic a natural hormone that helps regulate appetite and blood sugar.
    • Wegovy (semaglutide): Similar to Saxenda but administered once weekly, often leading to greater weight loss.
    • Ozempic (semaglutide): Primarily for type 2 diabetes but also aids weight loss.
    • Mounjaro (tirzepatide): Combines two hormones for enhanced weight loss and blood sugar control.

Other Weight Loss Medications:

  • Qsymia (phentermine/topiramate): Combines appetite suppressant and anti-seizure medication.
  • Contrave (naltrexone/bupropion): Combines opioid blocker and antidepressant to reduce cravings.
  • Orlistat (Alli, Xenical): Prevents fat absorption in the intestines.

Non-Medication Alternatives

  • Lifestyle Modifications:
    • Diet: Focus on whole foods, portion control, and balanced nutrition.
    • Exercise: Incorporate both cardiovascular and strength training into your routine.
    • Behavior Modification: Address emotional eating and develop healthy habits.
  • Surgical Interventions: For severe obesity, consider options like gastric bypass or sleeve gastrectomy.
  • Medical Supervision: Regular check-ups, monitoring, and support from healthcare professionals are crucial.

Choosing the Right Medicine for Diabetes

Selecting the best option depends on various factors:

  • Overall health: Consider underlying medical conditions.
  • Weight loss goals: Determine the desired amount of weight loss.
  • Lifestyle: Evaluate your ability to adhere to medication regimens or lifestyle changes.
  • Risk tolerance: Weigh the potential benefits and side effects of different options.

Saxenda has emerged as a useful drug in managing type 2 diabetes and aiding in weight loss. Combining medication with favorable lifestyle changes can often lead to optimal results.

Disclaimer: This information is intended for general knowledge and informational purposes only and does not constitute medical advice. Always consult with a healthcare professional for personalized guidance.

What is the Cost of Saxenda?

Medication Typical Price (USD) Our Price (USD)
Saxenda 18mg/3mL (5 pens) $1,430.00 $515.00

Without insurance: The exact price will depend on your pharmacy, but it’s generally considered a costly medication.  

With insurance: The cost can be more manageable. Many insurance plans cover Saxenda, but coverage varies. You might have a co-pay or deductible to meet before your insurance kicks in. Additionally, the manufacturer often offers patient assistance programs that can help reduce the cost for eligible patients.

Saxenda Storage Guidelines

Proper storage of Saxenda pens is crucial to maintain the medication’s effectiveness.

Before First Use:

  • Refrigerate: Store Saxenda pens in the refrigerator between 36°F to 46°F (2°C and 8°C) until the first use.
  • Avoid Freezing: Freezing Saxenda pens can damage the medication and render it ineffective.

After First Use:

  • Refrigerate or Room Temperature: Once used, a pen can be stored either in the refrigerator 36°F to 46°F (2°C and 8°C) or at room temperature below 86°F (30°C).
  • One-Month Limit: After opening a pen, use it within one month, even if medication remains.
  • Protect from Light: Always keep the pen cap on when not in use to protect the medication from light.

Additional Tips:

  • Avoid Extreme Temperatures: Do not expose Saxenda pens to excessive heat or cold.
  • Discard Properly: When finished with a pen, dispose of it safely according to local regulations.
  • Check Expiration Date: Always check the expiration date on the pen before use. Do not use Saxenda after the expiration date.
  • Monitor for Changes: Inspect the pen for any signs of damage, discoloration, or particles before use. If you notice any abnormalities, discard the pen.

The Best Foods To Eat On Saxenda

Saxenda can be a powerful tool for weight loss when combined with a healthy diet and regular exercise. The beauty of Saxenda is that it doesn’t tie you down to a strict diet plan. Instead, it empowers you to focus on certain foods that can enhance your weight loss journey and manage potential side effects.

Nutrient-Rich Foods

  • Lean proteins: Chicken, fish, tofu, beans, and lentils provide essential amino acids for muscle repair and satiety.
  • Whole grains: Brown rice, quinoa, whole-wheat bread, and oats offer sustained energy and fiber.
  • Fruits and vegetables: Packed with vitamins, minerals, and fiber, they promote overall health and aid digestion.
  • Healthy fats: Found in avocados, nuts, and olive oil, they support nutrient absorption and satiety.

Tips for Managing Side Effects

  • Nausea: Opt for bland foods like crackers, toast, or rice.
  • Digestive issues: Increase fiber intake gradually and stay hydrated.
  • Appetite suppression: Listen to your body and eat when genuinely hungry.

Foods to Limit

While not strictly prohibited, reducing your intake of processed foods, sugary drinks, and excessive amounts of saturated and unhealthy fats can support your weight loss goals.

NOTE: You’re not alone on this journey. Individual needs vary, and for personalized dietary advice, don’t hesitate to consult with a healthcare professional or registered dietitian. They’re here to support you every step of the way.

Campaign for Personal Prescription Importation

Millions of Americans use licensed Canadian pharmacies annually, to purchase their daily prescription medications at an affordable price. We believe that all Americans have a right to affordable medications.